Decoding unknown complexes

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Research Description

In a collaboration with the group of Theresa Carlomagno at EMBL Heidelberg the Utrecht group of Alexandre Bonvin has now officially extended HADDOCK to support up to 20 separate molecules, expanding its capabilities as truly integrated structure analysis platform able to very simply and effectively calculate the structure of large complexes (e.g. the protein-RNA complex illustrated in the figure) on the basis of diverse experimental data. We hope in a near future to release a new version of our HADDOCK web portal that will support this new version, together with cryo-EM restraints among others.