How do proteins meet?

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Research Description

The group of Prof. Ubbink (Leiden University), in collaboration with Prof. Luchinat (University of Florence), has develloped a new approach to characterize encounter states of protein complexes. Using paramagnetic NMR spectroscopy and advanced computational methods, it was possible to map the encounter state orientations and identify which encounters are futile and which lead to product complex formation. The results help to understand how proteins manage to form specific complexes quickly.